Libido

Sexual Health, Libido & Arousal

PT-141.

Bremelanotide combined with Oxytocin in a sublingual ODT. PT-141 works on the brain's melanocortin pathways, distinct from PDE5 inhibitors. Supports desire, arousal, and intimacy in men and women.

from $83 /mo equiv.

Buy one one-time, or save $198 with the 3-month plan, billed once. Provider consultation and free expedited shipping included.

Choose your plan

3-MonthRecommended

24 ODTs · $249 billed once

$83/mo

Save $198

Monthly

8 ODTs · one-time, no auto-renew

$149

Start your consultation

8 PT-141 (Bremelanotide 2mg) + Oxytocin 40IU ODTs

Sublingual route, no water needed

Licensed provider consultation included

Discreet, plain packaging

Free expedited shipping

Benefits

Desire that starts
in the brain.

PT-141 works upstream of the body's response. Instead of acting on blood vessels, it acts on the brain's melanocortin receptors, supporting desire and arousal at the source.

Acts on the brain

Bremelanotide stimulates the melanocortin pathway, distinct from PDE5 inhibitors that work on blood vessels.

Desire and arousal

Supports libido directly. Useful when ED medications alone aren't enough.

Men and women

Prescribed for both. Bremelanotide has been studied for low desire in women and is prescribed for men and women when appropriate.

Oxytocin bonding

Combined with low-dose oxytocin, the bonding/connection hormone, for added intimacy.

Sublingual ODT

Dissolves under the tongue. No water needed, no pills to swallow.

Provider review

Every order is reviewed by a licensed provider. PT-141 has unique contraindications that must be screened.

What's Included

Everything you need,
delivered.

Every plan includes the medication, provider consultation, ongoing care, and discreet shipping. The 3-month plan covers your full prescription on one consult.

PT-141 + Oxytocin ODT

8 sublingual tablets monthly. Bremelanotide 2mg + Oxytocin 40IU per dose. Dissolve 1 tablet 45 minutes before intimacy. Maximum 1 in any 24 hours, 8 per month.

Provider consultation

Licensed provider screens for blood pressure issues, mental health considerations, and other PT-141-specific contraindications.

Discreet shipping

Plain packaging. Free expedited shipping.

Ongoing care

Dose adjustment, dosing schedule questions, or new symptoms, message your provider anytime.

CLYR Journal

Want the full clinical guide?

PT-141 (Bremelanotide): Central Libido Peptide Therapy — Unlike PDE5 drugs that act peripherally, PT-141 is a melanocortin receptor agonist that works through brain pathways for desire, a different mechanism from PDE5 treatments.

Read the article →

FAQs

Common questions.

PT-141 (Bremelanotide) works through the brain's melanocortin pathway, supporting desire and arousal. PDE5 inhibitors like sildenafil and tadalafil work on blood vessels, supporting erection but not libido. Many patients use them together.

Yes. PT-141 works through the same central desire pathways in men and women, and bremelanotide has been studied for low sexual desire in premenopausal women. The CLYR formulation is compounded and available to men and women when prescribed by a licensed provider.

Most patients feel effects within 30-60 minutes of dissolving the ODT. Effects typically last 4-6 hours.

PT-141 supports natural desire and arousal but does not force a response. Sexual context and stimulation still matter.

Most common are temporary nausea, flushing, and a headache. Rare but possible: temporary increase in blood pressure, darkened skin spots with extended use. Your provider will discuss risks at consultation.

Anyone with uncontrolled hypertension, recent heart attack, severe cardiovascular disease, or pregnant women should not use PT-141. Patients on certain antidepressants should also avoid it.