Methylene blue, prescribed and compounded for you.

A synthetic compound made in 1876, originally as a fabric dye, and the first fully synthetic drug ever used in medicine. Hospitals still use it today as an antidote for methemoglobinemia (a condition where red blood cells cannot release oxygen properly) and as a dye in surgery, and it sits on the World Health Organization's list of essential medicines. In the body it works as a redox molecule, carrying electrons the way your mitochondria do when they make energy. At CLYR it is a pharmaceutical-grade compound your provider can prescribe, made into 5, 25, 50 or 100mg capsules by a licensed U.S. 503A pharmacy.

No. The blue bottle at the pet store is industrial-grade dye for fish and it can carry contaminants, including heavy metals. CLYR's capsules are compounded from USP pharmaceutical-grade methylene blue, the same grade hospitals use, by a licensed pharmacy to a provider's prescription. Never take an aquarium or laboratory product.

Methylene blue has been studied for over a century, and in recent years mostly for how it interacts with mitochondria and the brain. Much of that research is early, small or still in animals, so it is an active area of study rather than a settled one. CLYR does not make claims about what it will do for you. Your provider can talk through what is and is not known at your dose.

A licensed provider in your state reviews your questionnaire, including every medication you take, and decides whether methylene blue is appropriate and at what strength. Nothing ships without that review. If they decide it is not a fit, you are refunded in full.

That is your provider's call. Most start at 25mg, one capsule each morning for 30 days. If the first month goes well and your provider agrees, the next 30 days can step to 50mg, then 100mg. The 5mg capsule is the gentle entry for people who want to start low.

Methylene blue can be alerting, so it is taken in the morning with water rather than later in the day. One capsule, once a day, is the whole routine.

Yes. Blue-green urine is expected while you take methylene blue. It is the compound leaving the body and it is harmless. Rarely, it can tint tears or the whites of the eyes faintly for a short time.

Anyone taking an SSRI, SNRI, MAOI, tricyclic antidepressant, certain opioid pain medications, St. John's Wort or another serotonergic medication, because of the risk of serotonin syndrome. Anyone with G6PD deficiency. Anyone pregnant, trying to conceive or breastfeeding. Anyone allergic to methylene blue or to dyes. Severe kidney or liver disease is reviewed by your provider. The screening asks about every one of these, and the first four are hard stops.

Each bottle is 30 capsules, billed once; nothing renews on its own. Your provider writes the script with refills, so when you are ready for the next month, at the same strength or the next step up, reordering is one tap from your portal and the pharmacy fills it from the prescription on file.

Tracked, in a plain box with no product name on the outside, shipping included. Available in most states, usually within a few business days of provider approval.

A licensed pharmacy makes the capsules to your provider's prescription, for you, rather than pulling a mass-produced product off a shelf. Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety or effectiveness. CLYR's capsules are compounded from pharmaceutical-grade methylene blue by a licensed U.S. 503A pharmacy.

Strength and source. Capsules sold over the counter top out around 10 to 12mg; 25mg to 100mg is prescription territory, written by a provider who has reviewed your medications, and made to pharmaceutical standards rather than as a supplement. Elsewhere, 15 to 25mg typically runs $100 to $199 a month on a membership; here each strength is a single purchase with the price on the page.