Apomorphine is a dopamine D2 agonist that facilitates erection through central nervous system pathways involved in sexual arousal. Subcutaneous apomorphine (brand withdrawn in US) caused nausea; low-dose sublingual combinations with tadalafil 22 mg aim for synergistic effect: apomorphine for initiation, tadalafil for sustained vasodilation over 24 to 36 hours.

Compounded 22 mg / 2 mg troches are telehealth-standard "dual on-demand" doses. Apomorphine nausea is dose-dependent; take on empty stomach sublingually. Contraindicated with nitrates and caution with antihypertensives. Not FDA-approved as combination product.

CLYR Health offers tadalafil + apomorphine troches as a preview sexual health SKU.